Yiqun Xia Selected Research

Thioredoxin Reductase 1

1/2020	Isodeoxyelephantopin Inactivates Thioredoxin Reductase 1 and Activates ROS-Mediated JNK Signaling Pathway to Exacerbate Cisplatin Effectiveness in Human Colon Cancer Cells.
12/2019	Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells.
1/2019	Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS.
1/2019	Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.
5/2016	Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.
4/2016	EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Yiqun Xia Research Topics

Disease

16	Neoplasms (Cancer) 01/2021 - 03/2015
10	Stomach Neoplasms (Stomach Cancer) 12/2019 - 03/2015
4	Colonic Neoplasms (Colon Cancer) 01/2020 - 01/2019
3	Body Weight (Weight, Body) 12/2019 - 01/2019
1	Squamous Cell Carcinoma of Head and Neck 06/2020
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Lung Neoplasms (Lung Cancer) 01/2017
1	Inflammation (Inflammations) 01/2017

Drug/Important Bio-Agent (IBA)

9	CurcuminIBA 06/2020 - 03/2015
6	Thioredoxin Reductase 1IBA 01/2020 - 04/2016
5	Biological ProductsIBA 01/2019 - 03/2015
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 04/2016
3	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 01/2019
2	SesquiterpenesIBA 01/2020 - 01/2019
2	LactonesIBA 01/2020 - 01/2019
2	Insulin (Novolin)FDA Link 12/2019 - 05/2019
2	piperlongumineIBA 12/2019 - 05/2016
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2019 - 01/2019
2	AlkaloidsIBA 12/2019 - 05/2016
2	WZ35 compoundIBA 05/2019 - 03/2015
2	WZ26IBA 01/2019 - 01/2016
2	erastinIBA 01/2019 - 05/2016
2	EnzymesIBA 05/2016 - 04/2016
2	SelenocysteineIBA 05/2016 - 04/2016
2	AntioxidantsIBA 05/2016 - 04/2016
1	Everolimus FDA Link 01/2021
1	Auranofin (Ridaura)FDA Link 01/2021
1	JNK Mitogen-Activated Protein KinasesIBA 01/2021
1	MTOR InhibitorsIBA 01/2021
1	TOR Serine-Threonine KinasesIBA 01/2021
1	Oxidants (Oxidizing Agents)IBA 06/2020
1	MK 2206IBA 06/2020
1	Apoptosis Regulatory ProteinsIBA 06/2020
1	isodeoxyelephantopinIBA 01/2020
1	DiarylheptanoidsIBA 05/2019
1	Glutathione (Reduced Glutathione)IBA 01/2019
1	p38 Mitogen-Activated Protein KinasesIBA 01/2019
1	alantolactoneIBA 01/2019
1	plumbaginIBA 01/2018
1	NaphthoquinonesIBA 01/2018
1	Fluorouracil (Carac)FDA LinkGeneric 04/2016
1	diphenyl (biphenyl)IBA 04/2016
1	Antineoplastic Agents (Antineoplastics)IBA 04/2016
1	BromidesIBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	Da0324IBA 01/2016
1	Adenosine Triphosphate (ATP)IBA 04/2015
1	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 04/2015
1	Caspase 3 (Caspase-3)IBA 04/2015
1	Proteins (Proteins, Gene)FDA Link 04/2015
1	Masoprocol (Actinex)FDA Link 04/2015

Therapy/Procedure

6	Therapeutics 06/2020 - 04/2015
1	Drug Therapy (Chemotherapy) 01/2019
1	Traditional Medicine (Folk Remedies) 01/2018